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Korean Journal of Anesthesiology 1993;26(3):535-540.
DOI: https://doi.org/10.4097/kjae.1993.26.3.535   
The Effect of Anesthetic Duration of Epinephrine and Morphine Mixture with Local Anesthetics Simultaneously on Spinal Anesthesia.
Duk Hee Sohn, Sun Mee Jin, Soung Kyung Cho, Sang Hwa Lee
Department of Anesthesiology, Taegu Catholic University School of Medicine, Taegu, Korea.
Abstract
The effect of anesthetic duration of epinephrine and morphine mixture with hyperbaric tetracaine on spinal anesthesia was studied at Tague Catholic University Hospital. Fifty-two pa- tients, ASA physical status I-II, were selected randomly and divided them into 4 groups as follows: Group A; Only 0.5% hyperbaric tetracaine 14 mg injection. Group B; Mixture of 0.5% hyperbaric tetracaine 14 mg and morphine 0.15 mg injection. Group C; Mixture of 0.5% hyperbaric tetracaine l4 mg and epinephrine 0.2 mg injection. Group D; Mixture of 0.5% hyperbaric tetracaine 14 mg, morphine 0.15 mg and epinephrine 0.2 mg injection. The results of motor block onset, motor block duration, sensory block onset and sensory block duration were as follows: 1) Motor block onset; There were no statistical differences between each groups. 2) Motor block duration; The duration of motor blocks were significantly longer in group C and D than group A. The duration of motor block was significantly longer in group D than group B. 3) sensory block onset; There were no statistical differences between each groups. 4) Sensory block duration, The duration of sensory blocks were significantly longer in group D than group A, B and C. These results suggested that the effect of anesthetic duration of epinephrine and morphine mixture with local anesthetics simultaneously on spinal anesthesia were more prolonged than tetracaine injeetion only and injection of tetracaine, epinephrine mixture.
Key Words: Spinal anesthesia; Epinephrine; Morphine; Duration of anesthetic action


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