| The Effect of the Continuous Intravenous Infusion of Magnesium for the Treatment of Postherpetic Neuralgia -A case report-. |
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Hyun Park, Jung In Lee, Jang Ho Roh, Duck Mi Yoon |
1Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea. dmyoon@yumc.yonsei.ac.kr
2Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea. |
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| Abstract |
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Postherpetic neuralgia (PHN) is a chronic pain syndrome associated with the reactivation of a primary varicella zoster virus infection and is one of the most serious complication of herpetic zoster. The clinical features of PHN are ongoing pain accompanied by allodynia, hyperalgesia, and paresthesia. Current treatment options aimed at relieving the symptoms of PHN include oral agents, such as, opioid, NSAIDs, antidepressants, anticonvulsants. And local anesthetics with steroids are used for subcutaneous infiltration, somatic nerve block, sympathetic nerve block and epidural nerve block. However, in some cases, the pain does not respond to this treatment. We report a case in which a patient suffering from PHN did not respond to conventional therapy, but in whom continuous intravenous infusion of magnesium and physiologic N-methyl-D-aspartate (NMDA) receptor antagonist, reduced severe pain. |
| Key Words:
magnesium; NMDA receptor; postherpetic neuralgia |
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