| The Trial of Continuous Intravenous Infusion of Magnesium in Patients with Postherpetic Neuralgia Refractory in Conventional Treatment: A report of 2 cases. |
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Yong Kwan Cheong, Tai Yo Kim, Ju Hwan Lee |
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Department of Anesthesiology and Pain Medicine, School of Medicine, Wonkwang University, Iksan, Korea. ykfolder@naver.com |
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| Abstract |
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Postherpetic neuralgia is one of the most troublesome diseases in pain clinics. The N-methyl-D-aspartate (NMDA) receptor antagonist, magnesium, reduces the level of neuropathic pain and hyperalgesia in patients with postherpetic neuralgia. Magnesium has been shown to exert a physiological block of the ion channel on the NMDA receptor, thereby preventing extracellular calcium ions from entering the cell and contributing to secondary neuronal changes.
Accordingly, we attempted to administer a continuous intravenous infusion of magnesium, which resulted in a decrease in the VAS without side effects. |
| Key Words:
magnesium; neuropathic pain; NMDA receptor antagonist; postherpetic neuralgia |
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