| Unilateral Spinal Anesthesia with Hyperbaric Levobupivacaine and Bupivacaine for Lower Limb Surgery. |
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Se Jung Lee, Keum Young So, Byung Sik Yu |
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Department of Anesthesiology and Pain Medicine, Chosun University School of Medicine, Gwangju, Korea. bsbyou@chosun.ac.kr |
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| Abstract |
BACKGROUND
Levobupivacaine is the isolated S-enantiomer of bupivacaine and may be a favorable alternative to bupivacaine. The author evaluated the clinical efficacy of levobupivacaine relative to bupivacaine in spinal anesthesia.
METHODS
The author randomly allocated 40 ASA physical status I or II patients undergoing lower limb surgery to do unilateral spinal anesthesia with 8% glucose bupivacaine 4 mg (n = 20) or 8% glucose levobupivacaine 4 mg (n = 20).
Spinal anesthesia was performed at the L3-4 interspace using a 25-gauge Whitacre spinal needle. The lateral decubitus position was maintained for fifteen minutes after injection.
RESULTS
Thirty minutes after injection, unilateral sensory block was present in 60% and 40% of cases, and unilateral motor block was observed in 90% and 85% in levobupivacaine and bupivacaine group, respectively. Levobupivacaine group had no differences as compared to bupivacaine group for spinal block resolution.
CONCLUSIONS
It was concluded that 8% glucose levobupivacaine 4 mg and 8% glucose bupivacaine 4 mg provided similar spinal block for lower limb surgery without hemodynamic unstability. |
| Key Words:
bupivacaine; levobupivacaine; unilateral spinal anesthesia |
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