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Korean Journal of Anesthesiology 2006;50(6):S68-S70.
DOI: https://doi.org/10.4097/kjae.2006.50.6.S68   
Severe Oropharyngeal Angioedema Caused by Propofol: A case report.
Chul Ho Shin, Young Hee Lee, Young Min Kim, Se Hun Park, Iel Yong Sung, Seong Won Choi, Soon Eun Park
1Department of Anesthesiology and Pain Medicine, Ulsan University School of Medicine, Ulsan, Korea. gamju@yahoo.co.kr
2Department of Oral & Maxillofacial Surgery, Ulsan University School of Medicine, Ulsan, Korea.
3Department of Internal Medicine, Ulsan University School of Medicine, Ulsan, Korea.
Abstract
Although propofol is thought to be a relatively safe intravenous anesthetic with regard to histamine release reactions, anaphylactoid reactions to propofol may sometimes occur, especially in patients with a history of allergy, atopy, or asthma. Here we report a patient with allergies to sesame leaves and cold medications who experienced an anaphylactic reaction with severe oropharyngeal edema a few minutes after receiving propofol (Anepol(R)). This finding suggests that propofol should be used with caution in patients with a history of allergy. Because profound airway edema can occur, the airway should be evaluated before extubation of the trachea.
Key Words: airway; anaphylactic reaction; oropharyngeal edema; propofol


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