| Effects of Enflurane on Pulse Transit Time. |
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Seong Wan Baik, Yeong Seo Park, Soo Young Yae, Gye Rock Jeon, Byeong Cheol Choi, Dong Keun Jung |
1Department of Anesthesia and Pain Medicine, College of Medicine, Pusan National University, Korea. swbaik@pusan.ac.kr
2Department of Biomedical Engineering, Pusan National University, Korea.
3Department of Biomedical Engineering, Choonhae College, Korea.
4Department of Biomedical Engineering, College of Medicine, Dong-A University, Korea. |
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| Abstract |
BACKGROUND
In Anesthetic state, many hemodynamic parameters including blood pressure, heart rate and arterial compliance are changed. Moreover pulse transit time (PTT) is influenced by heart rate, blood pressure changes, and the compliance of the arteries.
METHODS
In this study, we investigated PTT changes in patients under enflurane anesthesia. PTT of the finger was measured by photoplethysmography (PPG) and electrocardiography (ECG). PTT values were calculated as the time interval between the peak of the ECG R wave and the peak of the second derivatived of the PPG in the finger tip.
RESULTS
ECG amplitude and heart rate increased reflecting hemodynamic chnages after enflurane anesthesia, and the PTT increased after enflurane anesthesia treatment by 16.68 ms (n = 24). Moreover, PTT was found to be inversely proportion to aging.
CONCLUSIONS
The increase of PTT in the finger due to relaxation of the arterial wall muscle after enflurane anesthesia was used as an indicator of sympathetic block on muscle tone. This result suggests that PTT is strongly related with anesthetic state. And PTT may be one of useful surrogative methods for anesthetic monitoring, but PTT is unfortunately only qualitative. |
| Key Words:
anesthesia; enflurane; photoplethysmography; pulse transit time |
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