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Korean Journal of Anesthesiology 2001;41(6):792-795.
DOI: https://doi.org/10.4097/kjae.2001.41.6.792   
Epidural Block of Bupivacaine and Mexiletine for Erythromelalgia.
Soo Kyung Park, Kyung Ream Han, Young Seok Lee, Hae Shin Hyun, Chan Kim
1Pain Clinic, Department of Anesthesiology, Ajou University School of Medicine, Suwon, Korea. anesk@madang.ajou.ac.kr
2Department of Anesthesiology, Pocheon Chung Moon University School of Medicine, Seoul, Korea.
3Department of Anesthesia, Kangnam General Hospital, Seoul, Korea.
Abstract
Erythromelalgia is a rare disease characterized by palmar and plantar erythema, burning pain and local increase in temperature. Secondary erythromelalgia most commonly appears secondary to myeloproliferative disorders, essential thrombocytosis and polycythemia vera. The pain associated with erythromelalgia is often severe and recalcitrant. So far no properly performed therapeutic trials have been published. We present a case of erythromelalgia of both hands and feet in a 52 year old man. A twice daily cervical and lumbar epidural block of mepivacaine 0.5% and mexiletine 100 mg given orally resuletd in complete resolution of the syndrome. After 3 months, the symptom recurred mildly.
Key Words: Anesthetic techniques: epidural; Disease: erythromelalgia; Anesthetics, local: mepivacaine; Pharmacology: mexiletine


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