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Korean Journal of Anesthesiology 1997;32(5):745-749.
DOI: https://doi.org/10.4097/kjae.1997.32.5.745   
Induction of Anesthesia with Low-Dose Midazolam and Thiopental.
Young Du Na, Young Ho Jang, Jung Kil Chung
1Department of Anesthesiology, Keimyung University, School of Medicine, Taegu, Korea.
2Department of Anesthesiology, College of Medicine, Seoul National University, Seoul, Korea.
Abstract
BACKGROUND
This study was undertaken to evaluate the hemodynamic response of midazolam-thiopental coinduction technique compared with thiopental or midazolam induction after tracheal intubation.
METHODS
60 patients were divided into 3 groups. Group I thiopental 5 mg/kg induction groups: Group II, midazolam 0.2 mg/kg induction group: Group III 2 mg/kg of thiopental was injected intravenously to each patient 2min after 0.02 mg/kg of midazolam injected. After tracheal intubation, blood pressure and heart rate were measured for 5 minutes at 1 minute interval.
Results
There were not significant differences in systolic, diastotic, mean arterial pressure and heart rate in 3 groups.
CONCLUSIONS
Low dose midazolam-thiopental coinduction can be a useful method for induction because of same hemodynamic changes as to thiopental or midazolam alone.
Key Words: Anesthetics; intravenous; midazolam; thiopental


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