Induction of Anesthesia with Low-Dose Midazolam and Thiopental. |
Young Du Na, Young Ho Jang, Jung Kil Chung |
1Department of Anesthesiology, Keimyung University, School of Medicine, Taegu, Korea. 2Department of Anesthesiology, College of Medicine, Seoul National University, Seoul, Korea. |
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Abstract |
BACKGROUND This study was undertaken to evaluate the hemodynamic response of midazolam-thiopental coinduction technique compared with thiopental or midazolam induction after tracheal intubation. METHODS 60 patients were divided into 3 groups. Group I thiopental 5 mg/kg induction groups: Group II, midazolam 0.2 mg/kg induction group: Group III 2 mg/kg of thiopental was injected intravenously to each patient 2min after 0.02 mg/kg of midazolam injected. After tracheal intubation, blood pressure and heart rate were measured for 5 minutes at 1 minute interval. Results There were not significant differences in systolic, diastotic, mean arterial pressure and heart rate in 3 groups. CONCLUSIONS Low dose midazolam-thiopental coinduction can be a useful method for induction because of same hemodynamic changes as to thiopental or midazolam alone. |
Key Words:
Anesthetics; intravenous; midazolam; thiopental |
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