| Activated Coagulation Time (ACT) Differences between Arterial and Venous Blood Samples in Patients with Open Heart Surgery. |
|
Byung Moon Ham, Yong Lak Kim, Sang Chul Lee, Jin Ho Lee, Myung Hee Kim, Dae Hyun Jo |
|
|
|
|
|
|
|
| Abstract |
BACKGROUND
Activated coagulation time (ACT) is commonly used to guide heparin and protamine dosing during cardiovascular surgery. There are many factors that influence the ACT such as time of test, hemodilution, temperature, aprotinin and etc. We considered the other factor that influence the ACT, the route of blood sample.
METHODS
This study included 40 patients who were scheduled for cardiac surgery. Whole blood was sampled through arterial and central venous line at 10 minutes after surgical incision and heparin administration. The ACT was measured with Hemochron 801 blood coagulation timer with 12 mg of celite surface activator.
RESULTS
At 10 minutes after surgical incision and heparin administration, arterial blood and venous blood ACTs were 127 20, 537 214 seconds and 118 18, 496 145 seconds respectively (p<0.05).
CONCLUSIONS
We conclude that the venous blood ACT is more less than arterial blood ACT during cardiovascular surgery. |
| Key Words:
Blood, arterial blood, coagulation, heparin, venous blood; Monitoring, activated coagulation time |
|
PDF Links
Full text via DOI
Download Citation
