| A Case of Withdrawal Symptom after Injection of Nalbuphine in a Chronically Morphine-Dependent Patient. |
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Kwang Tae Cho, Sang Chul Lee, Kwang Won Yum, Seok Kon Kim, Dong Hee Kim |
1Department of Anesthesiology, Seoul National University Medical College, Seoul, Korea.
2Department of Anesthesiology, Seoul National University Dental College, Seoul, Korea. |
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| Abstract |
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Nalbuphine, a mixed agonist-antagonist type opioid, can precipitate abstinence syndrome in opioid-dependent patients especially in large doses. We can prevent this syndrome by avoiding the injection of agonist-antagonist type opioid to the patient who already has used opioid for a long time, and the method of relatively small dose increments in its use.
We experienced a case of opioid withdrawal symptom in chronically morphine-administered patient via epidural catheter after using intramuscular nalbuphine for analgesia.
The symptom was promptly relieved by intravascular morphine injection without any problems. |
| Key Words:
Withdrawal Symptom; Nalbuphine; Morphine |
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